ceesdekker Can Be Fun For Anyone
ceesdekker Can Be Fun For Anyone
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Nanotechnology presents An array of opportunities to contribute to biology. Right here I will present examples in which nanofabrication – the opportunity to make confined buildings with Proportions at will – is made use of to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transportation of macromolecules
Around the similar time, the group of Paul McEuen, who was then based for the University of California, Berkeley, confirmed very similar benefits on ropes of bundled nanotubes. With regards to the wrapping angle, nanotubes can come in metallic or semiconducting variants, a prediction that we and Charles Lieber’s team at Harvard University independently verified utilizing scanning tunnelling spectroscopy experiments.
Sculpting nano-electrodes which has a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Our investigate ranges from the biophysics of DNA to artificial cells and further than. Be sure to take a look underneath for the spectrum of our present-day jobs.
We use nanofabricated microfluidic buildings to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement with the molecular and cellular degree. Our tasks consist of the following:
Example (one) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in gray, the rim on the pore is highlighted in red, and also a 3D rendering from the movement from the DNA rod is shown.
The rotors harness Electrical power from the nanoscale water and ion ceesdekker.net move that is definitely produced by a static chemical or electrochemical potential gradient during the nanopore, that happen to be set up via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-Arrange and function autonomously in physiological disorders, suggesting solutions to constructing energy-transducing motors at nanoscale interfaces.
Bulk-floor coupling identifies the mechanistic relationship concerning Min-protein patterns in vivo and in vitro
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Nanoscientist Cees Dekker is surely an amiable and flamboyant guy who seems Substantially youthful compared to 62 years he essentially is – stylish glasses, psychedelic shirt, partaking smile – although not a single to waste time. He usually takes his time, but no more than essential.
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2013, managed shaping of live bacterial cells into arbitrary designs; and discovery of spontaneous fluctuations within the handedness of histone tetrasomes